Which zone is involved in chondrogenesis?

Which zone is involved in chondrogenesis?

• A. Maturation zone
• B. Chondrogenic zone
• C. Calcification zone
• D. Proliferative zone

Answer: (B)

Chondrogenesis is the process of cartilage formation from mesenchymal cells, as those cells commit to the chondrocyte lineage and begin producing the cartilaginous matrix. The region specialized for this activity is the chondrogenic zone, where mesenchymal cells condense and differentiate into chondroblasts that secrete cartilage matrix and populate the developing cartilage. This zone reflects the active formation of cartilage, which is exactly what chondrogenesis entails. Other zones reflect later steps: proliferative zone mainly expands chondroblasts in columns; maturation (hypertrophic) zone involves chondrocyte enlargement and preparation for mineralization; calcification zone begins mineral deposition; ossification zone is where cartilage is replaced by bone.

Chondrogenesis is the process of cartilage formation from mesenchymal cells, as those cells commit to the chondrocyte lineage and begin producing the cartilaginous matrix. The region specialized for this activity is the chondrogenic zone, where mesenchymal cells condense and differentiate into chondroblasts that secrete cartilage matrix and populate the developing cartilage. This zone reflects the active formation of cartilage, which is exactly what chondrogenesis entails. Other zones reflect later steps: proliferative zone mainly expands chondroblasts in columns; maturation (hypertrophic) zone involves chondrocyte enlargement and preparation for mineralization; calcification zone begins mineral deposition; ossification zone is where cartilage is replaced by bone.