Which cell synthesizes bone matrix?

Which cell synthesizes bone matrix?

• A. Osteoclasts
• B. Osteocytes
• C. Chondrocytes
• D. Osteoblasts

Answer: (D)

Osteoblasts are the bone-forming cells responsible for synthesizing the organic part of the bone matrix. They line the surfaces of bone and produce osteoid, which is rich in type I collagen and other proteins. This organic matrix then becomes mineralized with calcium phosphate to give bone its strength. Osteoblasts originate from mesenchymal stem cells and, as they secrete matrix and become embedded in it, they can mature into osteocytes, which stay in the bone to maintain tissue. The other cells have different roles: osteoclasts resorb bone, and chondrocytes produce cartilage rather than bone matrix. Osteocytes are mature cells within bone that help monitor and regulate remodeling rather than forming new matrix.

Osteoblasts are the bone-forming cells responsible for synthesizing the organic part of the bone matrix. They line the surfaces of bone and produce osteoid, which is rich in type I collagen and other proteins. This organic matrix then becomes mineralized with calcium phosphate to give bone its strength. Osteoblasts originate from mesenchymal stem cells and, as they secrete matrix and become embedded in it, they can mature into osteocytes, which stay in the bone to maintain tissue. The other cells have different roles: osteoclasts resorb bone, and chondrocytes produce cartilage rather than bone matrix. Osteocytes are mature cells within bone that help monitor and regulate remodeling rather than forming new matrix.