Which cell resorbs bone tissue during remodeling?

Master the BCT Lab Practical 1 Test. Prepare with detailed flashcards and insightful multiple choice questions, complete with feedback and rationales. Ace your exam!

Multiple Choice

Which cell resorbs bone tissue during remodeling?

Explanation:
Osteoclasts resorb bone tissue during remodeling. These large, multinucleated cells attach to the bone surface and create a sealed resorption pit. They secrete acid to dissolve the mineral component and deploy proteolytic enzymes (like cathepsin K) to break down the organic matrix. This resorption clears old or damaged bone so osteoblasts can later lay down new bone in the same area, continuing the cycle. By contrast, osteoblasts form new bone, osteocytes are mature bone cells embedded in the matrix that help sense load and regulate remodeling, and chondrocytes form cartilage rather than bone.

Osteoclasts resorb bone tissue during remodeling. These large, multinucleated cells attach to the bone surface and create a sealed resorption pit. They secrete acid to dissolve the mineral component and deploy proteolytic enzymes (like cathepsin K) to break down the organic matrix. This resorption clears old or damaged bone so osteoblasts can later lay down new bone in the same area, continuing the cycle. By contrast, osteoblasts form new bone, osteocytes are mature bone cells embedded in the matrix that help sense load and regulate remodeling, and chondrocytes form cartilage rather than bone.

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