Nissl substance is found in which part of a multipolar motor neuron?

Nissl substance is found in which part of a multipolar motor neuron?

• A. Axon
• B. Dendrites
• C. Myelin sheath
• D. Cell body

Answer: (D)

Nissl substance are clusters of rough endoplasmic reticulum with ribosomes that handle the neuron’s protein synthesis. In a multipolar motor neuron, these structures are concentrated in the cell body (soma) and, to some extent, in the proximal portions of dendrites, supporting the high demand for producing membrane proteins and neurotransmitter-related proteins. They are not present in the axon or its myelin sheath, since those areas have fewer ribosomes and rely on proteins made in the soma. So, the most prominent location is the cell body.

Nissl substance are clusters of rough endoplasmic reticulum with ribosomes that handle the neuron’s protein synthesis. In a multipolar motor neuron, these structures are concentrated in the cell body (soma) and, to some extent, in the proximal portions of dendrites, supporting the high demand for producing membrane proteins and neurotransmitter-related proteins. They are not present in the axon or its myelin sheath, since those areas have fewer ribosomes and rely on proteins made in the soma. So, the most prominent location is the cell body.